Two patients with acute renal failure and streptococcal erysipela are
reported. In both cases, renal biopsy showed acute interstitial nephri
tis with a predominantly mononuclear infiltrate. Beta lactam antibioti
c without steroid therapy was followed by complete recovery of renal f
unction. It seems likely that some cases of AlN related to infection a
re erroneously attributed to antibiotic hypersensitivity.