We evaluated two children with pulmonary atresia for coil embolization
of aortopulmonary collateral vessels after placement of palliative ao
rtopulmonary shunts. To determine vessel distribution and lung perfusi
on prior to collateral embolization, perfusion scintigraphy with techn
etium 99m-labeled macroaggregated albumin assessed pulmonary blood flo
w before and after balloon wedge catheter occlusion of the collaterals
. In the first patient we found no perfusion defect during collateral
occlusion, and we proceeded with embolization. In the second child, pe
rfusion scintigraphy during occlusion of the collateral vessels demons
trated a filling defect, and embolization was not performed, thus avoi
ding the creation of a potential perfusion defect in this patient. Ass
essing the physiologic significance of aortopulmonary collateral vesse
ls by utilizing temporary balloon occlusion of the collateral vessels
and concurrent perfusion scintigraphy as an adjunct to selective angio
graphy can provide a significant contribution to the safety and accura
cy of coil embolization.