Duplex sonography was used to measure diameters of the common femoral,
superficial femoral, and popliteal veins in 56 patients followed for
more than 6 months after DVT and in 17 normal subjects. Diameter chang
es with Valsalva's maneuver were also measured as an index of venous c
ompliance. Among patients with unilateral thrombosis, segments with re
sidual disease were 0.07 to 0.28 cm smaller than the contralateral dis
ease-free side (p <0.05 for CFV and SFV) with a diameter index (ipsila
teral/contralateral diameter) significantly less than that of normal s
ubjects. In contrast, completely recanalized segments were not signifi
cantly different from the contralateral side and had diameter indices
indistinguishable from normal subjects. Distensibility with Valsalva's
maneuver was not significantly different from normal in DVT patients
with either resolved or residual disease. Venous diameter does decreas
e following DVT, but returns to normal following complete recanalizati
on and is not associated with chronic venous compliance changes.