SCP APPLICATION OR B15 STIMULATION ACTIVATES CAPK IN THE ARC MUSCLE OF APLYSIA

Authors
HOOPER SL PROBST WC CROPPER EC KUPFERMANN I WEISS KR
Citation
Sl. Hooper et al., SCP APPLICATION OR B15 STIMULATION ACTIVATES CAPK IN THE ARC MUSCLE OF APLYSIA, Brain research, 657(1-2), 1994, pp. 337-341
Citations number
21
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
657
Issue
1-2
Year of publication
1994
Pages
337 - 341
Database
ISI
SICI code
0006-8993(1994)657:1-2<337:SAOBSA>2.0.ZU;2-4
Abstract
Application of small cardioactive peptide (SCP) or stimulation of moto rneuron B15 increases the level of activated cAMP-dependent protein ki nase (cAPK) in the ARC muscle. SCP application also appears to induce a translocation of cAPK between different subcellular compartments of the ARC muscle and this translocation is also induced by cAMP addition to muscle homogenates. These results suggest that the actions of SCP in the Aplysia ARC neuromuscular system are mediated via the cAPK sign al transduction pathway.