PEPTIDE-BOND FORMATION VIA CATALYTIC ANTIBODIES - SYNTHESIS OF A NOVEL PHOSPHONATE DIESTER HAPTEN

Authors
SMITH AB TAYLOR CM BENKOVIC SJ HIRSCHMANN R
Citation
Ab. Smith et al., PEPTIDE-BOND FORMATION VIA CATALYTIC ANTIBODIES - SYNTHESIS OF A NOVEL PHOSPHONATE DIESTER HAPTEN, Tetrahedron letters, 35(37), 1994, pp. 6853-6856
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
37
Year of publication
1994
Pages
6853 - 6856
Database
ISI
SICI code
0040-4039(1994)35:37<6853:PFVCA->2.0.ZU;2-D
Abstract
Phosphonate diester 2, a hapten recently employed to induce the first monoclonal catalytic antibodies capable of catalyzing peptide bond for mation, was synthesized via elaboration of scalemic alpha-amino phosph onate 4.