TREATMENT OF STIFF-MAN SYNDROME WITH INTRAVENOUS IMMUNOGLOBULIN

Authors
AMATO AA CORNMAN EW KISSEL JT
Citation
Aa. Amato et al., TREATMENT OF STIFF-MAN SYNDROME WITH INTRAVENOUS IMMUNOGLOBULIN, Neurology, 44(9), 1994, pp. 1652-1654
Citations number
32
Categorie Soggetti
Clinical Neurology
Journal title
Neurology → ACNP
ISSN journal
00283878
Volume
44
Issue
9
Year of publication
1994
Pages
1652 - 1654
Database
ISI
SICI code
0028-3878(1994)44:9<1652:TOSSWI>2.0.ZU;2-O
Abstract
Stiff-man syndrome (SMS) is a rare disorder characterized by progressi ve rigidity, stiffness, and spasms of axial and extremity muscles. The etiology of SMS is unknown, but evidence suggests a possible autoimmu ne basis. The recent successful use of intravenous immunoglobulin (IVI G) in treating various autoimmune neuromuscular disorders led us to tr y IVIG in an uncontrolled pilot study on three patients. All three sho wed subjective and objective improvement.