ANALGESIC EFFECT OF SALMON-CALCITONIN SUPPOSITORIES IN PATIENTS WITH BONE PAIN

A double-blind, placebo-controlled study was performed to evaluate the analgesic effect of rectal synthetic salmon calcitonin (sCT) 100 IU c ompared with placebo in 60 patients suffering from bone pain secondary to osteoporosis or to lumbar spine osteoarthritis. Patients recorded daily their pain intensity by means of a visual analog scale. Results showed gradual pain relief in the sCT-treated group starting from day 7 of treatment, while pain was unmodified in the placebo group. At the end of the study, 88% of patients in the sCT group were pain free.