Mass independent renormalization group functions in massive theories a
re related to normalization properties of the Green functions in the a
symptotic region, where mass effects are neglected. In this special fo
rm the renormalization group invariance is restricted to the asymptoti
c region and consequently mass effects cannot be recovered by a integr
ation of the renormalization group equation. It is shown, that mass in
dependence results in the limit of a large normalization point, whenev
er a Callan-Symanzik equation exists and contains the same differentia
l operators as the renormalization group equation.