BIOMEDICAL APPLICATION OF AN ISOTOPE SELECTIVE NONDISPERSIVE INFRAREDSPECTROMETER FOR (CO2)-C-13 AND (CO2)-C-12 CONCENTRATION MEASUREMENTSIN BREATH SAMPLES

Authors
HAISCH M HERING P SCHADEWALDT P BROSICKE H BRADEN B KOLETZKO S STEFFEN C
Citation
M. Haisch et al., BIOMEDICAL APPLICATION OF AN ISOTOPE SELECTIVE NONDISPERSIVE INFRAREDSPECTROMETER FOR (CO2)-C-13 AND (CO2)-C-12 CONCENTRATION MEASUREMENTSIN BREATH SAMPLES, Isotopenpraxis, 30(2-3), 1994, pp. 253-257
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear","Nuclear Sciences & Tecnology
Journal title
Isotopenpraxis → ACNP
ISSN journal
00211915
Volume
30
Issue
2-3
Year of publication
1994
Pages
253 - 257
Database
ISI
SICI code
0021-1915(1994)30:2-3<253:BAOAIS>2.0.ZU;2-M
Abstract
A newly developed isotope selective nondispersive infrared (NDIR) spec trometer for the measurement of (CO2)-C-13 and (CO2)-C-12 concentratio ns in breath samples was applied as a low cost and very simple to oper ate alternative to isotope ratio mass spectrometry (IRMS). We used thi s device for several biomedical applications ([C-13]urea breath test, [C-13]leucine metabolism, [C-13]methacetin catabolism of rats) and fou nd that the results agree very well with IRMS.