LOCALIZED PLEURAL MESOTHELIOMA WITH ELEVATION OF HIGH-MOLECULAR-WEIGHT INSULIN-LIKE GROWTH-FACTOR-II AND HYPOGLYCEMIA

Authors
SAKAMOTO T KANESHIGE H TAKESHI A TSUSHIMA T HASEGAWA S
Citation
T. Sakamoto et al., LOCALIZED PLEURAL MESOTHELIOMA WITH ELEVATION OF HIGH-MOLECULAR-WEIGHT INSULIN-LIKE GROWTH-FACTOR-II AND HYPOGLYCEMIA, Chest, 106(3), 1994, pp. 965-967
Citations number
8
Categorie Soggetti
Respiratory System
Journal title
Chest → ACNP
ISSN journal
00123692
Volume
106
Issue
3
Year of publication
1994
Pages
965 - 967
Database
ISI
SICI code
0012-3692(1994)106:3<965:LPMWEO>2.0.ZU;2-B
Abstract
Recurrent hypoglycemia occurred in a 48-year-old woman with a localize d pleural mesothelioma. During hypoglycemia, serum high molecular weig ht insulin-like growth factor II (IGF-II) was elevated. The tumor also contained a high level of high molecular weight IGF-II. We propose th at the primary cause of the hypoglycemia in this patient was the high molecular weight IGF-II produced by the tumor.