Cellular reaction and pigment deposits on the intraocular lens were ev
aluated by biomicroscopy in 220 eyes which had undergone estracapsular
cataract extraction and implantation of a posterior chamber intraocul
ar lens 3 months previously. No cells or pigment were observed on the
intraocular lens in 32% of the eyes, while small cells and/or pigment
were found in 32% and giant cells with or without pigment and small ce
lls were seen in 35%. In a sample of 28 eyes the clinical findings cor
related with the findings in specular microphotographs. The correspond
ing percentages were 32, 36 and 32% in biomicroscopy and 14, 36 and 50
% in specular microphotography. The giant cell reaction was notably (p
< 0.001) associated with the presence of exfoliation. Previous ocular
diseases and operations did not increase the frequency of cellular re
action.