TUR-P IN LOCAL ISCHEMIA - BENEFITS AND RI SKS

Transurethral resection of the prostate (TUR-P) is still the gold stan dard in the treatment of benign prostatic hyperplasia (BPH). Because t he TUR-P morbidity has remained unchanged at 18% for years, it seemed reasonable to look for therapeutic alternatives. The most critical poi nt is the possibility of blood loos with a need for substitution even if TUR-P is done by a highly experienced urologist. By infiltrating th e prostate with a vasoconstrictive agent we looked for a technique to reduce blood loss and resection time. In 19/35 patients, preoperative infiltration of the prostate with 5 IE Ornipressin dissolved in 20 ml NaCl was performed transurethrally. 16 patients served as controls (no rmal TUR-P). In the Ornipressin group, blood loss was significantly lo wer than in the control group. Compared with the conventional method, resection time could be significantly reduced. Resection could be done under excellent optical conditions. There were no severe side effects . Short-term increase in blood pressure and reflex bradycardia could b e treated.