Traumatic and vascular brain injuries consist of acute episodes follow
ed by development of chronic components of varying magnitude and durat
ion whose potentials for recovery differ. We discuss a case of closed
head injury in which interventional hyperbaric oxygen (HBO) with singl
e photon emission computed tomography were used as aids in determining
the presence of recoverable neurons, to follow therapeutic progress,
and to determine the end point of therapy. This case also shows the su
ccessful use of intensive HBO as a therapeutic modality.