CLONING AND CHARACTERIZATION OF A FULL-LENGTH CDNA CODING FOR OVINE ALDOLASE-B FROM FETAL MESONEPHROS

Authors
GIANQUINTO L PAILHOUX EA BEZARD J SERVEL N KIRSZENBAUM M COTINOT C
Citation
L. Gianquinto et al., CLONING AND CHARACTERIZATION OF A FULL-LENGTH CDNA CODING FOR OVINE ALDOLASE-B FROM FETAL MESONEPHROS, Biochimica et biophysica acta, N. Gene structure and expression, 1219(1), 1994, pp. 223-227
Citations number
12
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1219
Issue
1
Year of publication
1994
Pages
223 - 227
Database
ISI
SICI code
0167-4781(1994)1219:1<223:CACOAF>2.0.ZU;2-S
Abstract
An ovine aldolase B cDNA was isolated from mesonephros (29 dpc). The s equence covers 1649 nucleotides. Comparison with human liver aldolase B cDNA shows a homology of about 86%. The deduced amino acid sequence is composed of 364 residues and exhibits 92% homology to the human pro tein. Northern blot analysis and in situ hybridization data show that during the first third of gestation in sheep, aldolase B expression is restricted to the mesonephros.