STEADY-STATE TRANSCRIPT LEVELS OF THE TYPE-II HEXOKINASE AND TYPE-1 GLUCOSE-TRANSPORTER IN HUMAN TUMOR-CELL LINES

Authors
SHINOHARA Y YAMAMOTO K KOGURE K ICHIHARA J TERADA H
Citation
Y. Shinohara et al., STEADY-STATE TRANSCRIPT LEVELS OF THE TYPE-II HEXOKINASE AND TYPE-1 GLUCOSE-TRANSPORTER IN HUMAN TUMOR-CELL LINES, Cancer letters, 82(1), 1994, pp. 27-32
Citations number
24
Categorie Soggetti
Oncology
Journal title
Cancer letters → ACNP
ISSN journal
03043835
Volume
82
Issue
1
Year of publication
1994
Pages
27 - 32
Database
ISI
SICI code
0304-3835(1994)82:1<27:STLOTT>2.0.ZU;2-L
Abstract
The steady state transcript levels of two hexokinase isozymes and type 1 glucose transporter in human tumor cell lines were analyzed. In Hep G2 cells, both type II hexokinase and type 1 glucose transporter were highly expressed. However, in cell lines A431 and HeLa, in which the e xpression level of type 1 glucose transporter was lower than that in H epG2 cells, the amount of type II hexokinase transcript was almost neg ligible.