ALLOGENEIC MARROW TRANSPLANTATION FOR MYELODYSPLASTIC SYNDROME COMPLICATING AUTOLOGOUS BONE-MARROW TRANSPLANTATION

Citation
S. Bashir et al., ALLOGENEIC MARROW TRANSPLANTATION FOR MYELODYSPLASTIC SYNDROME COMPLICATING AUTOLOGOUS BONE-MARROW TRANSPLANTATION, Cancer investigation, 12(5), 1994, pp. 484-487
Citations number
36
Categorie Soggetti
Oncology
Journal title
ISSN journal
07357907
Volume
12
Issue
5
Year of publication
1994
Pages
484 - 487
Database
ISI
SICI code
0735-7907(1994)12:5<484:AMTFMS>2.0.ZU;2-C
Abstract
A patient with refractory relapsed Hodgkin's disease underwent an auto logous bone marrow transplant in July 1987 and achieved remission of H odgkin's disease. He had complete hematological recovery but developed pancytopenia 3 years post bone marrow transplantation with morphologi cal evidence of myelodysplasia. High-dose cyclophosphamide, 200 mg/kg, chemotherapy followed by an allogeneic bone marrow transplant from a HLA-matched sibling was performed in April 1991 with complete hematolo gical recovery. Allogeneic bone marrow transplantation was thus used s uccessfully to treat a potential complication of autologous bone marro w transplantation.