The effectiveness of some genetically engineered microorganisms in the
control of plant disease pathogens is widely acknowledged. These biop
esticides, so far, pose less danger to the environment. However, littl
e attention has been paid to the potential benefit of the use of exome
tabolites of some microorganisms in spite of their known activity and
high biodegradability. A total of 1108 fungal metabolite extracts obta
ined from different strains of micromycetes cultured in two different
liquid media (malt extract and yeast saccharose) were tested for antif
ungal activity. The target organisms were Colletotrichum musae, Drechs
lera spicifera, Fusarium oxysporum, Geotrichum candidum, Pyricularia o
ryzae, Drechslera oryzae and Gerlachia oryzae. Percentage mycelial gro
wth inhibition activities varied widely with the different taxonomic g
roups. Extracts from Aspergillus and Penicillium spp. consistently sho
wed the highest activity. A greater number of micromycetes produced ac
tive extracts in a liquid yeast extract saccharose medium than in a li
quid malt extract medium. Mycelial growth inhibition diameters were al
so greater in assays with extracts from the yeast extract saccharose m
edium. The results generally demonstrated fungal metabolite extracts a
s potential sources of agricultural chemical input.