G. Vaiopoulos et al., LACK OF RESPONSE TO CORTICOSTEROIDS AND PULSE CYCLOPHOSPHAMIDE THERAPY IN COGANS-SYNDROME, Clinical rheumatology, 13(1), 1994, pp. 110-112
A 17-year-old girl with Cogan's syndrome is described. Total and irrev
ersible hearing loss occurred which was unresponsive to corticosteroid
s and immunosuppressive therapy. The girl died a year later from subar
achnoid haemorrhage. The lethal prognosis in Cogan's syndrome despite
the available treatment is emphasized.