LOPERAMIDE INTOXICATION IN A 7-WEEK-OLD PUP

A 7-w-old Samoyed-cross pup was presented with central nervous system signs approximately 18 h following administration of the second of 2 d oses of loperamide. Circling, vocalization, head pressing and unreacti ve pupils were present. There was no history of trauma. improvement wa s seen shortly following administration of activated charcoal and 0.2 mi naloxone. Naloxone treatment was repeated at 2-h intervals over 12- h. Approximately 20 h following the initial clinical evaluation, the p uppy was released to the owner for home care and observation.