TISSUE LIPOPEROXIDATION AND GLUTATHIONE-PEROXIDASE ACTIVITY IN PUROMYCIN AMINONUCLEOSIDE INJECTED RATS

Authors
PEDRAZACHAVERRI J AREVALO AE
Citation
J. Pedrazachaverri et Ae. Arevalo, TISSUE LIPOPEROXIDATION AND GLUTATHIONE-PEROXIDASE ACTIVITY IN PUROMYCIN AMINONUCLEOSIDE INJECTED RATS, International Journal of Biochemistry, 26(9), 1994, pp. 1139-1145
Citations number
32
Categorie Soggetti
Biology
Journal title
International Journal of Biochemistry → ACNP
ISSN journal
0020711X
Volume
26
Issue
9
Year of publication
1994
Pages
1139 - 1145
Database
ISI
SICI code
0020-711X(1994)26:9<1139:TLAGAI>2.0.ZU;2-S
Abstract
1. Lipoperoxidation (LPx) and glutathione peroxidase (GPx) activity we re measured in kidney, liver, heart, lung, brain and testis from contr ol and puromycin aminonucleoside (PAN) injected rats on days 1-6, 8, 1 0, 16 and 22 after vehicle or PAN injection. 2. PAN-injected rats deve loped proteinuria on day 3. 3. In PAN-injected rats: (a) LPx increased in kidney, liver, lung, brain and testis before day 3 and in heart on day 3; (b) GPx activity increased in kidney, liver, heart, lung and t estis and diminished in brain on day 3 or after.