A. Hameed et Tj. Charles, CHOLINERGIC CRISIS FOLLOWING TREATMENT OF POSTOPERATIVE URINARY RETENTION WITH DISTIGMINE BROMIDE, British journal of clinical practice, 48(2), 1994, pp. 103-104
Distigmine bromide is a long-acting anticholinesterase, available for
the treatment of postoperative urinary retention. Its effectiveness is
unproven and administration may be hazardous. We describe a case in w
hich oral distigmine bromide was used for postoperative retention, res
ulting in a potentially life-threatening 'cholinergic crisis'. We revi
ew the literature and conclude that the use of oral distigmine bromide
in postoperative urinary retention is not justified.