C-ERBB-3 PROTEIN EXPRESSION IN HUMAN BREAST-CANCER - COMPARISON WITH OTHER TUMOR VARIABLES AND SURVIVAL

Authors
QUINN CM OSTROWSKI TL LANE SA LONEY DP TEASDALE J BENSON EA
Citation
Cm. Quinn et al., C-ERBB-3 PROTEIN EXPRESSION IN HUMAN BREAST-CANCER - COMPARISON WITH OTHER TUMOR VARIABLES AND SURVIVAL, Histopathology, 25(3), 1994, pp. 247-252
Citations number
21
Categorie Soggetti
Cytology & Histology",Pathology
Journal title
Histopathology → ACNP
ISSN journal
03090167
Volume
25
Issue
3
Year of publication
1994
Pages
247 - 252
Database
ISI
SICI code
0309-0167(1994)25:3<247:CPEIHB>2.0.ZU;2-A
Abstract
c-erbB-3 protein expression was investigated immunohistochemically in a series of 97 malignant breast tumours using the monoclonal antibody RTJ1. Twenty-eight cases (28.8%) showed c-erbB-3 overexpression, 31 ca ses (32%) showed normal levels of c-erbB-3 and 38 cases (39.2%) were c -erbB-3 negative, c-erbB-3 overexpression was positively but not signi ficantly related to negative lymph node status and survival over a l0- year follow-up period.