BACKGROUND: The aim of this study was to determine the use of blood sa
mples obtained through central venous catheters (CVC) in the diagnosis
of bacteremias in patients admitted to an intensive care unit (ICU).
METHODS: A prospective randomized study was carried out in which 125 b
lood samples obtained by CVC were compared with 125 samples simultaneo
usly obtained by venopuncture. RESULTS: In 105 sample pairs (84%) the
results of both samples were in agreement (Kappa index 0.61). The sens
itivity of the technique in the diagnosis of bacteremia was 76.5%, spe
cificity 86.8% positive predictive value 68.4% and negative predictive
value 90.8%. No differences were found in the efficacy of the techniq
ue carried out by venous punction or that of the samples obtained thro
ugh catheters inserted in subclavian, femoral and antecubital veins (p
=0.99). CONCLUSIONS: Blood cultures Obtained through central venous ca
theters constitute a technical alternative for the diagnosis of bacter
emia in cases in which venopunction in difficult or of doubtful asepsi
a.