Background Few data are available on the prevalence of hypertension in
Mexico.Methods and Results We compared the prevalence of mild hyperte
nsion (systolic blood pressure greater than or equal to 140 mm Hg and/
or diastolic blood pressure greater than or equal to 90 mm Hg and/or u
se of antihypertensive medications) in 1500 low-income Mexican America
ns who participated in the San Antonio Heart Study and 2280 low-income
Mexicans who participated in the Mexico City Diabetes Study, The crud
e prevalence of mild hypertension was 17.1% in Mexican men versus 24.4
% in Mexican American men (P=.001) and 17.4% in Mexican women versus 2
2.0% in Mexican American women (P=.005). After adjustment for age, bod
y mass index (BMI), waist-to-hip ratio (WHR), noninsulin dependent dia
betes mellitus (NIDDM), educational attainment, and percent native Ame
rican genetic admixture (Caucasian and native American), the odds rati
o (Mexico City/San Antonio) was 0.55 (95% CI, 0.39, 0.77; P<.001) in m
en and 0.81 (CI, 0.54, 1.12; P=.201) in women. In a pooled model inclu
ding both men and women, the odds ratio was 0.67 (95% CI, 0.53, 0.84;
P<.001). In the pooled model, city, age, female sex, NIDDM, BMI, WHR,
and low educational attainment were significantly related to the preva
lence of hypertension. Conclusions The causes for these differences in
hypertension prevalence are not known but may reflect a less moderniz
ed lifestyle in Mexico City, including greater physical activity, less
obesity, and the consumption of a high-carbohydrate, low-fat diet.