MOLECULAR CHARACTERIZATION OF A GENE THAT CONFERS 2-DEOXYGLUCOSE RESISTANCE IN YEAST

Authors
SANZ P RANDEZGIL F PRIETO JA
Citation
P. Sanz et al., MOLECULAR CHARACTERIZATION OF A GENE THAT CONFERS 2-DEOXYGLUCOSE RESISTANCE IN YEAST, Yeast, 10(9), 1994, pp. 1195-1202
Citations number
24
Categorie Soggetti
Microbiology,"Biothechnology & Applied Migrobiology",Biology
Journal title
Yeast → ACNP
ISSN journal
0749503X
Volume
10
Issue
9
Year of publication
1994
Pages
1195 - 1202
Database
ISI
SICI code
0749-503X(1994)10:9<1195:MCOAGT>2.0.ZU;2-D
Abstract
We have isolated a gene whose expression enables yeast cells to overco me the inhibition of growth produced by the presence of 2-deoxyglucose . The gene contains an open reading frame of 738 bp that may code for a protein of 27 100 Da. Cells carrying this gene contain high levels o f a specific 2-deoxyglucose-6-phosphate phosphatase. The expression of this phosphatase is increased by the presence of 2-deoxyglucose and i s constant along the growth curve. The sequence reported here has the GenBank accession number U03107.