RECENT ADVANCES IN LIPOPROTEIN AND ATHEROSCLEROSIS RESEARCH AT BAYLORCOLLEGE OF MEDICINE - APOLIPOPROTEIN-B, LIPOPROTEIN[A], AND TRANSPLANTATION ARTERIOPATHY

Citation
Cm. Ballantyne et al., RECENT ADVANCES IN LIPOPROTEIN AND ATHEROSCLEROSIS RESEARCH AT BAYLORCOLLEGE OF MEDICINE - APOLIPOPROTEIN-B, LIPOPROTEIN[A], AND TRANSPLANTATION ARTERIOPATHY, Texas Heart Institute journal, 21(1), 1994, pp. 48-55
Citations number
NO
Categorie Soggetti
Cardiac & Cardiovascular System
ISSN journal
07302347
Volume
21
Issue
1
Year of publication
1994
Pages
48 - 55
Database
ISI
SICI code
0730-2347(1994)21:1<48:RAILAA>2.0.ZU;2-L
Abstract
A multidisciplinary team approach with focused objectives characterize s research at Baylor College of Medicine into the causes, prevention, and treatment of atherosclerotic disease. Current clinical activities range from programs to modify lifestyle for the primary prevention of coronary artery disease to a large, angiographically monitored lipid-l owering trial. In basic research, much attention has been focused on t he plasma lipoproteins and their roles in atherogenesis. The current r eview highlights recent advances in ongoing basic research involving 1 ) apolipoprotein (apo) B, whose form apo B-100 serves as a ligand for the low-density lipoprotein receptor; 2) lipoprotein[a], elevated plas ma levels of which are predictive of atherosclerotic disease; and 3) t ransplantation arteriopathy, which impedes long-term survival of cardi ac transplant recipients.