GC QUANTITATIVE-DETERMINATION OF ILLICIT LSD

Several methods are used for the determination of LSD in forensic scie nce casework samples. One of these involving a shift in UV absorption maximum is considered too nonspecific to provide unequivocal confirmat ion of the presence of LSD. Currently, HPLC methods using fluorescence detectors are recommended for quantification and capillary GC/MS is c onsidered a good technique for the qualitative identification of the d rug. In this work we demonstrate the possibility of using capillary GC for the quantitative determination of LSD since this method is equall y sensitive but surely more flexible and rapid than the HPLC ones.