This study illustrates the use of the neural network approach in the p
roblem of diagnostic classification of resting 12-lead electrocardiogr
ams. A large electrocardiographic library (the CORDA database establis
hed at the University of Leuven, Belgium) has been utilized in this st
udy, whose classification is validated by electrocardiographic-indepen
dent clinical data. In particular, a subset of 3,253 electrocardiograp
hic signals with single diseases has been selected. Seven diagnostic c
lasses have been considered: normal, left, right, and biventricular hy
pertrophy, and anterior, inferior, and combined myocardial infarction.
The basic architecture used is a feed-forward neural network and the
backpropagation algorithm for the training phase. Sensitivity, specifi
city, total accuracy, and partial accuracy are the indices used for te
sting and comparing the results with classical methodologies. In order
to validate this approach, the accuracy of two statistical models (li
near discriminant analysis and logistic discriminant analysis) tune on
the same dataset have been taken as the reference piont. Several nets
have been trained, either adjusting some components of the architectu
re of the networks, considering subsets and clusters of the original l
earning set, or combining different neural networks. The results have
confirmed the potentially and good performance of the connectionist ap
proach when compared with classical methodologies.