Thirty-six subjects affected with hypersomnia associated with mood dis
orders, 31 with a diagnosis of dysthymia, 4 with a diagnosis of bipola
r disorder and one with a diagnosis of major recurrent depression unde
rwent standardized polysomnographic procedures including night 1, MSLT
and night 2 (uninterrupted). 36.1% of these subjects had a reduced or
intermediate mean sleep latency on the MSLT and 13.8% slept over 9 hr
at night. In addition 17 of these subjects underwent prolonged polyso
mnography during day 2. In comparison with eight subjects affected wit
h idiopathic hypersomnia, mean sleep latency on the MSLT was significa
ntly longer and total sleep time during night 2 and during night 2 plu
s day 2 was significantly lower in subjects affected with hypersomnia
associated with mood disorders. It is concluded that a positive diagno
sis of hypersomnia associated with a mood disorder requires both behav
ioral observation and polysomnography. Among these subjects there may
be subjects with well-documented hypersomnia and subjects with anergia
facilitating or mimicking sleep.