Study objective: To evaluate the effect of the Trendelenburg position
on oxygen transport in hypovolemic patients. Design: A prospective, se
lf-controlled sequential design. Interventions: All patients had indwe
lling pulmonary artery catheters, and hypovolemia was confirmed by a p
ulmonary artery wedge pressure of 6 mm Hg or less. Hemodynamic and oxy
gen transport variables were measured with the patient supine and agai
n ten minutes after placing the patient in the Trendelenburg position.
Setting: University-affiliated tertiary care surgical ICU. Type of pa
rticipants: Eight postoperative adults. Results: Mean arterial blood p
ressure increased from 64.9 4.9 to 75.6 +/- 3.5 mm Hg (P < .05), pulmo
nary artery wedge pressure increased from 4.6 +/- 1.1 to 7.9 +/- 0.8 m
m Hg (P < .05), and the systemic vascular resistance rose to 2,965 +/-
210 from 2,302 +/- 199 dyne . sec/cm5 (P < .05). There was no signifi
cant change in cardiac index, oxygen delivery, oxygen consumption, or
oxygen extraction ratio. Conclusion: The increase in blood pressure fr
om Trendelenburg position is not associated with an improvement in blo
od flow or tissue oxygenation.