Objective: The predictive value of a fetal biophysical profile was eva
luated in our high-risk population, compared with the predictive value
s of each parameter and of the combinations, and reviewed in light of
the literature. Methods: The study included 248 high-risk pregnancies.
The fetal biophysical profile was performed as described by Manning.
The timing and mode of delivery were decided on the basis of fetal, ob
stetric, and maternal factors by the unit looking after the patients.
Abnormal outcome was defined as intrapartum fetal distress and/or less
than 7 on the 5-min Apgar score. Results: The incidence of mortality
was one case in 252 births (3.97 per thousand). The collective morbidi
ty rate was 16.3%. Out of 42 with abnormal outcome, the score was 2 or
4 in 6 cases, 6 in 22 cases. The amniotic fluid variable had the high
est sensitivity rate. However, regarding specificity, all parameters h
ad the same high rate. Regarding the efficacy of the combination of va
riables, the highest sensitivity rate was in the combination of nonstr
ess test-amniotic fluid and fetal breathing movement-amniotic fluid, 5
7.1% and 56.3%, respectively. The sensitivity rate was 30.4% in the co
mbination of nonstress test-fetal breathing movements and 40.5% in the
combination of all parameters. Conclusion: The fetal biophysical prof
ile score is a useful test for fetal surveillance but is time consumin
g. Meanwhile, the combination of a nonstress test and amniotic fluid v
ariables is a reliable and time-saving method.