PURPOSE: To determine whether hemangiomas and malignant tumors can be
better differentiated at 1.5-T magnetic resonance imaging with use of
more heavily T2-weighted conventional spin-echo sequences. MATERIALS A
ND METHODS: Eighty-three patients with focal liver lesions (50 maligna
nt tumors, 24 hemangiomas, nine cysts) larger than 1 cm were studied w
ith a 3,000/80,160 sequence (repetition time msec/echo time [TE] msec)
. T2 relaxation times and lesion/liver signal intensity ratios at TEs
of 80 and 160 msec were measured. Receiver operating characteristic (R
OC) analyses of expert readers and quantitative measures were performe
d. RESULTS: T2 relaxation times demonstrated the best performance in d
istinguishing hemangiomas from malignant tumors (area under ROC curve
= .99 +/- .01). Mean T2 times were 76 msec +/- 11 for malignant tumors
, 142 msec +/- 40 for hemangiomas, and 341 msec +/- 38 for cysts. A cu
toff T2 value of 112 msec allowed discrimination between hemangiomas a
nd malignant tumors with a 97% accuracy, 100% sensitivity, and 92% spe
cificity. CONCLUSION: Hemangiomas and malignant tumors are better diff
erentiated with use of T2 relaxation times obtained with a more heavil
y T2-weighted sequence.