RADIATION-INDUCED ANGIOSARCOMA OF THE BREAST - CASE-REPORT AND REVIEWOF THE LITERATURE

Angiosarcoma is a rare, highly malignant soft tissue sarcoma that some times occurs in the breast as a late sequela of treatment for breast c ancer. The conventional treatment for radiation-induced angiosarcoma i s surgery, which is associated with a poor overall prognosis. We repor t a case of radiation-induced angiosarcoma of the intact breast that o ccurred 6 years after breast conservation therapy. Simple mastectomy w as performed; however, rapid chest wall recurrence of angiosarcoma ens ued. After salvage therapy with combined radiotherapy and hyperthermia , the patient has been disease-free for more than 3 years.