REGIOCONTROL OF FORMAL [3-ALKOXYOXAZOLES WITH DIETHYL OXOMALONATE(2] CYCLOADDITIONS OF 5)

Authors
SUGA H SHI XL IBATA T
Citation
H. Suga et al., REGIOCONTROL OF FORMAL [3-ALKOXYOXAZOLES WITH DIETHYL OXOMALONATE(2] CYCLOADDITIONS OF 5), Chemistry Letters, (9), 1994, pp. 1673-1676
Citations number
6
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
9
Year of publication
1994
Pages
1673 - 1676
Database
ISI
SICI code
0366-7022(1994):9<1673:ROF[WD>2.0.ZU;2-T
Abstract
Tin(IV) chloride-catalyzed formal [3 + 2] cycloadditions of 5-alkoxy-2 -(p-methoxyphenyl)- or 2-phenyloxazoles with diethyl oxomalonate gave 2-oxazoline-4,5,5-tricarboxylates in high regioselectivity. 4-Substitu ted 5-alkoxy-2-methyloxazoles showed a trend to shift the regioselecti vity to offer more 3-oxazoline-2,5,5-tricarboxylates in terms of regio selectivity than 2-oxazolines.