Pj. Paley et al., THE EFFECT OF SARTORIUS TRANSPOSITION ON WOUND MORBIDITY FOLLOWING INGUINAL-FEMORAL LYMPHADENECTOMY, Gynecologic oncology, 64(2), 1997, pp. 237-241
In spite of efforts to reduce complications associated with inguinal-f
emoral lymphadenectomy (IFL), morbidity continues to be substantial. W
e sought to assess the efficacy of sartorius transposition (ST) in red
ucing groin wound complications following IFL, in patients with vulvar
malignancy. The records of 101 patients with vulvar cancer undergoing
IFL through separate incisions between March 1975 and December 1994 w
ere examined. Sixty-two patients undergoing ST (group 1) were compared
to 38 who did not (group 2). The groups were similar with respect to
age, weight, tobacco/alcohol use, prior abdominal/vulvar surgery, prev
alence of diabetes, hypertension, or peripheral vascular disease, and
previous exposure to irradiation or chemotherapy. Additionally, there
was no significant difference with respect to extent of disease, incid
ence of macro-/microscopic groin metastases, use of groin drains, and
use of perioperative antibiotics or deep venous thrombosis prophylaxis
. Groin wound complications were less frequent in patients undergoing
ST (group 1). The incidence of groin cellulitis was 30% in group 1 com
pared with an incidence of 58% in group 2 (P = 0.011). Significant gro
in wound morbidity, defined as either wound breakdown or cellulitis, w
as seen less frequently in group 1 (41% vs 66%; P = 0.029). Employing
a multivariate analysis, only patient weight <150 lbs and performance
of ST were established as independently associated with a reduction in
groin morbidity following IFL (P = 0.0281 and P = 0.0075, respectivel
y). In conclusion, despite waning enthusiasm for its performance, ST a
ppeared to significantly reduce the incidence of wound morbidity after
IFL. Our data confirmed that separate incisions, and improved periope
rative antibiotics, have not eliminated the value inherent in this sur
gical modification. We suggest a prospective trial to further establis
h the benefit of sartorius transposition during IFL. (C) 1997 Academic
Press.