EFFICACY OF CLARITHROMYCIN IN ERADICATING HELICOBACTER-PYLORI

We reviewed reports on the efficacy of clarithromycin in eradicating H elicobacter pylori. Reports on dual and 1-week triple therapy that inc luded clarithromycin were analyzed to assess the eradication rates of H. pylori infection. Dual therapy with clarithromycin and a proton pum p inhibitor achieved eradication rates of 38%-83%, and 1-week triple t herapy with omeprazole, clarithromycin, and other antibiotics achieved eradication rates, of 80%-96%. The incidence of side effects with all regimens was low. Clarithromycin is useful for treatment of Ij. pylor i infection. One-week triple therapy that includes clarithromycin and a proton pump inhibitor effectively eradicates H. pylori.