PERIARTICULAR HYPEROSTOSIS AND RENAL-DISEASE IN 6 BLACK LEMURS OF 2 FAMILY GROUPS

Progressive, proliferative periosteal disease associated with renal di sease can develop in black lemurs (Eulemur macaco macaco), perhaps as the result of a heritable condition. Clinical signs in lemurs with pro gressive, proliferative periosteal disease associated with renal disea se differ from that described for animals with hypertrophic osteoarthr opathy in the distribution of lesions (predominantly metaphyseal rathe r than diaphyseal) and the organ systems involved (renal rather than t horacic or gastrointestinal). Histologic changes evident on postmortem examination of lemurs with progressive, proliferative periosteal dise ase associated with renal disease are identical to lesions described f or other animals with hypertrophic osteoarthropathy.