Considerable advances are occurring in the application of laparoscopic
techniques to gastrointestinal and hepatobiliary disorders. Following
studies in experimental animals, surgeons with an interest in gastrod
uodenal disease have now introduced laparoscopic techniques into curre
nt surgical practice. Elective intervention for peptic ulcer disease i
s currently being established, particularly in patients with proven ne
gative Helicobacter pylori (HP) status, or when eradication has proved
unsuccessful with various drug regimens. In addition, emergency lapar
oscopic intervention for perforation is gaining acceptance, with or wi
thout a definitive anti-ulcer procedure. Therapeutic endoscopy for ble
eding peptic ulcer may well be followed by anti-ulcer laparoscopic sur
gery in selected patients. Laparoscopic techniques have been utilized
for the treatment of Mallory Weiss tear, congenital hypertrophic pylor
ic stenosis, Dieulafoy's lesion, gastric trauma or volvulus and benign
gastric tumours. More ergonomic instruments are required before lapar
oscopic gastric resection becomes more widely acceptable. It is essent
ial that objective evaluation of variations on vagotomy themes be unde
rtaken in prospective clinical trials and that the safety and efficacy
of gastric resection procedures be substantiated if this renaissance
is to revolutionize gastroduodenal surgical practice.