SUCCESSFULLY TREATED POSTPARTUM LYMPHANGI OLEIOMYOMATOSIS

Immediately after delivery a 17-year-old Turkish primipara developed e dema, supraclavicular lymphoma and pleural effusion. CT-scans showed m assive abdominal and mediastinal lymphoma. Lymphangioleiomyomatosis (L AM) was diagnosed by supraclavicular and retroperitoneal biopsy and pr ogesterone receptors were documented in the tumor. There was no eviden ce of pulmonary involvement. 5 months' treatment with the LHRH-analogu e goserelin showed neither clinical improvement nor regression of LAM. Irradiation of the ovaries and the abdomen with 30.2 Gy was followed by amenorrhea without immediate tumor remission. A follow-up examinati on 1 year later revealed clinical improvement and CT scans showed 50% abdominal and mediastinal regression of LAM. 51/2 years after diagnosi s the asymptomatic patient is still in partial remission. Sucessful tr eatment of LAM is rare. We describe a case in which a major tumour red uction was documented by CT scanning.