HISTOENZYMATIC STUDY OF HUMAN RENAL TISSUE PRESERVATION .2. CATALASE ACTIVITY IN PROXIMAL TUBULAR CELLS IS UNCORRELATED WITH TRANSPLANT EVOLUTION

Authors
BENKOEL L CHAMLIAN A DIMARINO V BRISSE J CHOLLATNAMY A GULIAN JM BONGRAND P
Citation
L. Benkoel et al., HISTOENZYMATIC STUDY OF HUMAN RENAL TISSUE PRESERVATION .2. CATALASE ACTIVITY IN PROXIMAL TUBULAR CELLS IS UNCORRELATED WITH TRANSPLANT EVOLUTION, Cellular and molecular biology, 40(6), 1994, pp. 811-818
Citations number
35
Categorie Soggetti
Cytology & Histology",Biology
Journal title
Cellular and molecular biology → ACNP
ISSN journal
01455680
Volume
40
Issue
6
Year of publication
1994
Pages
811 - 818
Database
ISI
SICI code
0145-5680(1994)40:6<811:HSOHRT>2.0.ZU;2-#
Abstract
Enzyme histochemical activity of catalase, a peroxisomal enzyme involv ed in cellular antioxidant systems, was studied in proximal tubular ce lls of human renal transplants as a marker of ischemia-reperfusion inj ury in the prediction of the evolution of renal transplants. A low enz ymatic activity was observed in all renal biopsies performed at 30 min . reperfusion with no difference between the several evolution types o f renal transplants. Reduced catalase activity due to ischemia-reperfu sion injury could not be correlated with renal function or used as an index of renal function recovery.