Metastatic cancer to the thyroid gland is uncommon. In this report we
describe a patient with a malignant fibrous histiocytoma that metastas
ized to the thyroid, possibly to a preexisting thyroid nodule. A revie
w of the literature reveals that breast and lung carcinoma are the mos
t frequently identified sources of secondary thyroid carcinoma found a
t autopsy, while renal carcinoma comprises over 50% of secondary thyro
id malignancies discovered clinically. A number of authors suggest tha
t preexisting thyroid disease (i.e., multinodular goiter and thyroid n
odules) may provide a nidus for metastases to the thyroid gland.