Large-bore catheters for extracorporeal detoxification methods without
and with treated surface with silver or silicone were investigated af
ter removal with a scanning electron microscope and for bacterial colo
nization. In 42 large-bore catheters of three different materials, sma
ll deposits of fibrin and protein on the inner and outer surface were
seen. This second layer covered the entire surface after 3 days and in
creased to a thickness of 3 to 60 mum during the following days. Bacte
rial colonization was observed in 38.1%. In contrast to these results,
the catheters with the treated outer surface showed a very low thromb
ogenecity and a low contamination rate of 6.7%.