A ten-year retrospective review of 23 cases of documented spinal epidu
ral abscess in the cervical spine was undertaken to define the clinica
l features and establish current diagnostic and therapeutic criteria.
Diagnosis was made by magnetic resonance imaging or myelography. Risk
factors included intravenous drug abuse, diabetes mellitus, previous t
rauma, and a positive serologic test for the human immunodeficiency vi
rus. A bacterial agent was isolated in 21 cases (91%). Neurologic defi
cits were present in 20 of the cases (87%) at the time of diagnosis. E
rythrocyte sedimentation rate was elevated in all patients in whom it
was measured. All patients were treated with appropriate antibiotics,
usually for 6 to 8 weeks. Twenty-one patients underwent operative proc
edures using percutaneous aspiration (1 patient), the anterior approac
h (14 patients) or the posterior approach (4 patients), or a combinati
on of the two approaches (2 patients). Four of ten patients who initia
lly had less than antigravity strength were eventually ambulatory and
continent; in each case, operative decompression was performed within
36 hours of initial consultation. Three patients who had no initial ne
urologic deficits remained intact.