Experimental studies have confirmed the clinical impression that large
bilateral pleural effusions are able to raise the pressure in an othe
rwise hemodynamically insignificant pericardial effusion to a level su
fficient to produce right ventricular diastolic collapse (RVDC). The h
emodynamic consequences of this syndrome are not as severe as when the
intrapericardial pressure is raised to the same level by excess intra
pericardial fluid in the absence of pleural effusions. RVDC caused by
excess pleural fluid with a minor pericardial effusion is a false posi
tive indication for pericardial fluid drainage. Thoracentesis is more
appropriate.