Doppler echocardiography has greatly facilitated the assessment of pat
ients with compressive cardiac disease. Patients in whom cardiac tampo
nade or pericardial constriction are suspected should undergo a comple
te echocardiographic examination including careful Doppler analysis of
transmitral flow and inflow through the hepatic vein or superior vena
cava (SVC). Monitoring of both the electrocardiogram and the phase of
respiration are an integral part of this examination. Patients with c
ardiac tamponade exhibit a > 25% reduction in E wave velocity during t
he first inspiratory cardiac cycle; they exhibit predominant systolic
inflow through the hepatic vein or SVC (with a predominant X descent w
ith little or no Y descent). In constrictive pericarditis the pattern
of transmitral flow variation is comparable to that observed in cardia
c tamponade, however, a prominent Y descent is often observed on hepat
ic vein or SVC Doppler study. Similar changes with respiration may be
observed in mitral inflow in obese patients or in those with chronic o
bstructive pulmonary disease, however, in these conditions the nadir o
f E wave velocity is observed 2-3 cardiac cycles after the first inspi
ratory beat. Restrictive cardiomyopathy may produce a similar systemic
venous flow pattern, but increased inspiratory flow reversals and lac
k of respiratory variation in transmitral flow velocity distinguish it
from constrictive pericarditis.