PULMONARY INFILTRATION WITH EOSINOPHILIA AND INCREASED SERUM LEVELS OF SQUAMOUS-CELL CARCINOMA-RELATED ANTIGEN AND NEURON-SPECIFIC ENOLASE

We report a case of pulmonary infiltration with eosinophilia (PIE), as sociated with increased serum levels of squamous cell carcinoma-relate d antigen (SCC) and neuron specific enolase (NSE). The diagnosis of PI E was confirmed by examination of bronchoalveolar lavage fluid and spe cimens of transbronchial lung biopsy. It was suggested that PIE was pr obably induced by a course of amoxicillin for a sore throat. Corticost eroid therapy resulted in clinical improvement of symptoms, resolution of pulmonary infiltrates on chest roentgenogram and reduction in seru m levels of SCC and NSE.