S. Chu et Jr. Kennedy, INTRAEPITHELIAL PALATINE NERVE-ENDINGS AND THEIR REGULATION OF CILIARY ACTIVITY OF FROG PALATE EPITHELIUM, Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 175(4), 1994, pp. 505-518
1. Direct contact between intra-epithelial nerve endings and ciliated
cells was observed in frog (Rana pipiens) palate epithelium. 2. Electr
ical stimulation of the palatine nerve to the explant or the explant c
ulture induced an increase in ciliary beat frequency in explant and ou
tgrowth cells. 3. Atropine inhibited electrically stimulated ciliary b
eat frequency increase in the explant and outgrowth cells. 4. Gap junc
tional intercellular communication appears to be involved in the propa
gation of stimulated ciliary beat frequency increase from innervated t
o non-innervated ciliated cells.