STUDY OF PHARMACOKINETIC MODIFICATION OF MUTAGENESIS

Authors
REVAZOVA YA BRATSLAVSKY VA
Citation
Ya. Revazova et Va. Bratslavsky, STUDY OF PHARMACOKINETIC MODIFICATION OF MUTAGENESIS, VESTNIK ROSSIISKOI AKADEMII MEDITSINSKIKH NAUK, (1), 1993, pp. 14-19
Citations number
15
Categorie Soggetti
Medicine, General & Internal
Journal title
VESTNIK ROSSIISKOI AKADEMII MEDITSINSKIKH NAUK → ACNP
ISSN journal
08696047
Issue
1
Year of publication
1993
Pages
14 - 19
Database
ISI
SICI code
0869-6047(1993):1<14:SOPMOM>2.0.ZU;2-Y
Abstract
The mutagenic activity of some antitumor agents and the antituberculou s agent isoniazid was studied by using some methods for estimating mut ations on the Drosophilla, mammals, and human cells. It was shown that mutagenic effects could be modiffied by adding various auxiliaries to the formulations of the drugs. The mechanisms of modifications were e xamined by pharmacokinetic techniques.