2 SEPARATE PATHWAYS FOR CEREBELLAR LTD - NO-DEPENDENT AND NO-INDEPENDENT

Authors
HARTELL NA
Citation
Na. Hartell, 2 SEPARATE PATHWAYS FOR CEREBELLAR LTD - NO-DEPENDENT AND NO-INDEPENDENT, Behavioral and brain sciences, 19(3), 1996, pp. 453
Citations number
14
Categorie Soggetti
Psychology,"Psychology, Biological",Neurosciences,"Behavioral Sciences
Journal title
Behavioral and brain sciences → ACNP
ISSN journal
0140525X
Volume
19
Issue
3
Year of publication
1996
Database
ISI
SICI code
0140-525X(1996)19:3<453:2SPFCL>2.0.ZU;2-3
Abstract
Strong stimulation of parallel fibers (PFs) leads to localized calcium influx and a long-term depression (LTD) of PF responses at the site o f stimulation. These same stimuli also induce depression at spatially distant synapses to the same cell that is mediated by the diffusible m essenger nitric oxide (NO). The demonstration of two distinct forms of LTD provide an explanation for the absence of the NO/cGMP pathway in cultured cells.