ANALYSIS OF THE HUMTH01 ALLELE FREQUENCIES IN THE SPANISH POPULATION

Genetic marker typing based on DNA amplification by the polymerase cha in reaction (PCR) increasingly is being employed in forensic casework and for paternity testing. The allele frequencies were determined usin g PCR for 120 unrelated Spanish Caucasians for the locus HUMTH0H1. Six alleles were observed, with frequencies ranging from 0.013 (allele 11 ) to 0.254 (allele 10). The observed heterozygosity was 75.8%, and the power of discrimination is 0.92. The genotype distribution meets Hard y-Weinberg expectations.